A Critical Factor in Cellular Energy and Heart Health – BIGVITA (2025)

• May 29, 2025
• General
• 4 min read

Every second, trillions of biochemical reactions take place in the human body. These reactions power movement, repair damaged tissues, regulate metabolism, and sustain life. Behind all of this lies a highly sophisticated molecular network, and among its most essential players are coenzymes.

Among them, Coenzyme Q10 (CoQ10)stands out. It is a fat-soluble molecule naturally synthesized by the body and is often referred to as the “spark plug” of cellular energy. CoQ10plays a key role in both energy metabolismand antioxidant defense, particularly in high-energy-demand organs such as the heart, brain, and liver.

The Core Fuel for Cellular Energy

CoQ10is a central component of the electron transport chainwithin the mitochondria, the energy-producing structures of our cells. It drives the production of ATP (adenosine triphosphate), the body’s primary energy molecule.

When CoQ10 levels are insufficient, cellular energy productiondeclines significantly. This can lead to reduced stamina, fatigue, and even organ dysfunction.

Essential Support for the Heart and Brain

The heart and brainare the two most energy-intensive organs in the body. As a result, they rely heavily on CoQ10to meet their high metabolic demands.

In the heart, CoQ10 supports cardiovascular function, myocardial contraction, and vascular tone. In the brain, it fuels neurons and protects against oxidative stress, a key factor in neurodegeneration.

With age, the body’s natural ability to synthesize CoQ10declines. Tissue levels drop significantly after 40, contributing to fatigue, slower recovery, and reduced cardiovascular efficiency.

CoQ10 Production Slows with Age

Although CoQ10 is produced naturally, this capacity diminishes after age 30. Chronic stress, poor nutrition, and medications such as statinsmay further suppress CoQ10 levels.

Common symptoms of CoQ10 deficiencyinclude:

• Persistent fatigue and low energy
• Slower recovery from exertion
• Higher oxidative stress markers
• Declines in heart health

How to Supplement CoQ10 in Daily Life?

CoQ10 can be obtained in two main ways: through diet and through supplements.

1. From Food:
Natural sourcesof CoQ10 include animal-based foods such as beef, chicken, mackerel, and sardines, as well as plant-based options like spinach, broccoli, peanuts, and sesame seeds.

However, typical dietary intake only provides about 3–6 mg per day, which is far below the levels found to support energy metabolismand cellular protectionin clinical studies.

2. From Supplements:
CoQ10exists intwo forms: the oxidized form(ubiquinone) and the reduced form (ubiquinol). The key difference can be simply explained as this: ubiquinone is like a “raw material” that needs to be converted before use, while ubiquinol is the “finished product” that the body can absorb and utilize directly.

Ubiquinone must first be converted into ubiquinolin the body before it can be used. When we’re young and our metabolism is functioning well, this conversion is generally efficient. However, as we age, the body’s ability to convert ubiquinone declines significantly, which can reduce the effectiveness of supplementation.

Ubiquinolis the primary form of CoQ10 found in the body. It’s already in its active state and can be used by cells without any conversion. That makes it a better option for older adults, people who stay up late, live under long-term stress, experience slow physical recovery, or have weakened immune function.

Thought

From fueling every heartbeat to shielding cells from damage, Coenzyme Q10plays a foundational role in long-term health. As research into mitochondrial biologyadvances, CoQ10remains central to the discussion of energy, longevity, and cardiovascular support.

Reference:

1. Rabanal-Ruiz Y, Llanos-González E, Alcain F J. The Use of Coenzyme Q10 in Cardiovascular Diseases[J]. Antioxidants, 2021, 10(5): 755.

2. Mortensen S A, Rosenfeldt F, Kumar A, et al. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial[J]. JACC Heart Failure, 2014, 2(6): 641-649.

3. Littarru G P, Lambrechts P. Coenzyme Q10: Multiple benefits in one ingredient[J]. OCL – Oilseeds and Fats, Crops and Lipids, 2011, 18(2): 76-82.